Detection principle
Colorectal cancer is one of the most common malignant tumors of human digestive tract, ranking third in incidence rate and fifth in mortality among malignant tumors. According to the World Cancer Report 2020, in the past 20 years, the incidence rate of colorectal cancer in China has shown a rapid upward trend, and the incidence is young. Especially in urban areas, in the first tier cities, it is possible to surpass lung cancer and become the new king of cancer.
Although colorectal cancer has a high mortality rate, it is not scary. It takes 5-10 years from the initial stage to eventually mutate into colorectal cancer, and we have sufficient time to discover and treat it. Research has found that gene methylation occurs before cancer and is an important mechanism for cancer development, acting as a "switch" that regulates gene expression. Its stability and consistency are good, making it an ideal means of early screening for cancer. Therefore, abnormal methylation is a distinctive cancer signal. Abnormal gene methylation is closely related to the occurrence of cancer and can be used as a molecular marker for early cancer screening.